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More recent work includes publications on the conduct of PRO assessment within trials (PLOS One), issues surrounding ‘PRO Alerts’ (JAMA viewpoint, PLOS One) and PROs in Big data (JRSM). Putting patient-reported outcomes on the 'Big Data Road Map'.

Prof Calvert has worked on a number of clinical trials, most notably the Cardiac REychronisation in Heart Failure Trial (which demonstrated significant improvements in symptoms, quality of life and survival in patients receiving CRT). Kyte D, Reeve BB, Efficace F, Haywood K, Mercieca-Bebber R, King MT, Norquist JM, Lenderking WR, Snyder C, Ring L, Velikova G, Calvert M*.

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She has a current total grant income in excess of £7 million and is the cross-cutting theme lead for PROs research within major NIHR infrastructure including the Biomedical Research Centre, Surgical Reconstruction and Microbiology Research Centre, Clinical Research Facility (further awards £25 million) and the Institute for Translational Medicine.

Prof Calvert leads the Health Informatics and Patient Reported Outcomes (PROs) Research Group at the University of Birmingham, is an expert advisor to the NIHR West Midlands Research Design Service (patient reported outcomes/trials methodology), a NIHR CDRF Panellist, was a member of the International Society for Quality of Life Research (ISOQOL) Board of Directors, is co-Chair of the ISOQOL Best Practice for PROs in Clinical Trials Task force and Chairs the Applied Health Research Workstream/is a member of the Scientific Advisory Board within the Institute of Translational Medicine. Anker SD, Agewall S, Borggrefe M, Calvert M, Caro J, Cowie MR, Ford I, Paty JA, Riley JP, Swedberg K, Tavazzi L, Wiklund I, Kirchhof P The Importance of Patient Reported Outcomes: A Call for Their Comprehensive Integration in Cardiovascular Clinical Trials.

She has 120 peer reviewed publications in journals including the NEJM, BMJ, JAMA and the Lancet.

Her highly cited work has informed European Society of Cardiology guidelines, NICE and EMA guidance, was REF returned and the subject of an Impact Case Study.

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Her primary research interests are outcomes research, including the use of composite outcomes and best practice for patient reported outcome assessment in clinical trials and routine practice.